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miR4673 improves fitness profile of neoplastic cells by induction of autophagy

Therapeutic resistance of neoplasms is mainly attributed to gradual evolution of mutational profile(1). Here, we demonstrate a microRNA-mediated mechanism that effectively improves fitness of SKBR3 mammary carcinoma cells by cytoplasmic reprogramming. The reprogramming is triggered by endogenous miR...

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Detalles Bibliográficos
Autores principales:	Dökümcü, Kağan, Simonian, Mary, Farahani, Ramin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195512/ https://www.ncbi.nlm.nih.gov/pubmed/30341280 http://dx.doi.org/10.1038/s41419-018-1088-6

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