Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation

Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration. Although part of the opioid-induced itch is mediated centrally,...

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Detalles Bibliográficos
Autores principales: Melo, Helvira, Basso, Lilian, Iftinca, Mircea, MacNaughton, Wallace K., Hollenberg, Morley D., McKay, Derek M., Altier, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195532/
https://www.ncbi.nlm.nih.gov/pubmed/30341332
http://dx.doi.org/10.1038/s41598-018-33620-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195532/
https://www.ncbi.nlm.nih.gov/pubmed/30341332
http://dx.doi.org/10.1038/s41598-018-33620-7

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