Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes

Genome-wide association studies (GWAS) aim to identify genetic factors associated with phenotypes. Standard analyses test variants for associations individually. However, variant-level associations are hard to identify and can be difficult to interpret biologically. Enrichment analyses help address...

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Detalles Bibliográficos
Autores principales: Zhu, Xiang, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195536/
https://www.ncbi.nlm.nih.gov/pubmed/30341297
http://dx.doi.org/10.1038/s41467-018-06805-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195536/
https://www.ncbi.nlm.nih.gov/pubmed/30341297
http://dx.doi.org/10.1038/s41467-018-06805-x

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