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Relative positioning of Kv11.1 (hERG) K(+) channel cytoplasmic domain-located fluorescent tags toward the plasma membrane

Recent cryo-EM data have provided a view of the KCNH potassium channels molecular structures. However, some details about the cytoplasmic domains organization and specially their rearrangements associated to channel functionality are still lacking. Here we used the voltage-dependent dipicrylamine (D...

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Detalles Bibliográficos
Autores principales: Barros, Francisco, Domínguez, Pedro, de la Peña, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195548/
https://www.ncbi.nlm.nih.gov/pubmed/30341381
http://dx.doi.org/10.1038/s41598-018-33492-x