SB772077B, A New Rho Kinase Inhibitor Enhances Aqueous Humour Outflow Facility in Human Eyes

We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hy...

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Detalles Bibliográficos
Autores principales: Ashwinbalaji, Soundararajan, Senthilkumari, Srinivasan, Gowripriya, Chidambaranathan, Krishnadas, Subbaiah, Gabelt, B’ Ann T., Kaufman, Paul L., Muthukkaruppan, Veerappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195566/
https://www.ncbi.nlm.nih.gov/pubmed/30341380
http://dx.doi.org/10.1038/s41598-018-33932-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195566/
https://www.ncbi.nlm.nih.gov/pubmed/30341380
http://dx.doi.org/10.1038/s41598-018-33932-8

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