Cargando…

SB772077B, A New Rho Kinase Inhibitor Enhances Aqueous Humour Outflow Facility in Human Eyes

We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashwinbalaji, Soundararajan, Senthilkumari, Srinivasan, Gowripriya, Chidambaranathan, Krishnadas, Subbaiah, Gabelt, B’ Ann T., Kaufman, Paul L., Muthukkaruppan, Veerappan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195566/ https://www.ncbi.nlm.nih.gov/pubmed/30341380 http://dx.doi.org/10.1038/s41598-018-33932-8

Ejemplares similares

SB772077B (SB77) Alleviated the Aqueous Outflow Resistance Mediated by Cyclic Mechanical Stress in Perfused Human Cadaveric Eyes
por: Ashwinbalaji, Soundararajan, et al.
Publicado: (2020)

Assessment of differential intraocular pressure response to dexamethasone treatment in perfusion cultured Indian cadaveric eyes
por: Haribalaganesh, Ravinarayanan, et al.
Publicado: (2021)

Identification of glaucomatous optic nerve head changes in Indian donor eyes without clinical history
por: Senthilkumari, Srinivasan, et al.
Publicado: (2015)

A Comparative Genome-Wide Transcriptome Analysis of Glucocorticoid Responder and Non-Responder Primary Human Trabecular Meshwork Cells
por: Kathirvel, Kandasamy, et al.
Publicado: (2022)

Identification, quantification and age-related changes of human trabecular meshwork stem cells
por: Sundaresan, Yogapriya, et al.
Publicado: (2019)

Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells
por: Cong, Lin, et al.
Publicado: (2018)

Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-Responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment
por: Kathirvel, Kandasamy, et al.
Publicado: (2023)

What is the optimal glaucoma treatment: reducing aqueous humour production or facilitating its outflow?
por: Killer, Hanspeter E., et al.
Publicado: (2020)

Reduction in trabecular meshwork stem cell content in donor eyes with primary open angle glaucoma
por: Sundaresan, Yogapriya, et al.
Publicado: (2021)

On Inflammation of the Membrane of the Aqueous Humour of the Eye
por: Watson, Alexander
Publicado: (1845)

Short and long-term effect of dexamethasone on the transcriptome profile of primary human trabecular meshwork cells in vitro
por: Kathirvel, Kandasamy, et al.
Publicado: (2022)

Author Correction: Short and long-term effect of dexamethasone on the transcriptome profile of primary human trabecular meshwork cells in vitro
por: Kathirvel, Kandasamy, et al.
Publicado: (2022)

Endocannabinoids in aqueous humour of patients with or without diabetes
por: Richardson, Patrick, et al.
Publicado: (2020)

Repeated Evacuation of the Aqueous Humour in Diseases of the Eye
por: Sperino, Casimir
Publicado: (1866)

Penetration of Enrofloxacin in Aqueous Humour of Avian Eyes
por: Fuchs, Katrin, et al.
Publicado: (2022)

Observations on the Effects of Evacuating the Aqueous Humour in Inflammation of the Eyes
Publicado: (1808)

Proteomic analysis of the aqueous humour in eyes with pseudoexfoliation syndrome
por: Botling Taube, Amelie, et al.
Publicado: (2019)

Hsa-miR-150-5p inhibits Wnt-β-catenin signaling in human corneal epithelial stem cells
por: Kalaimani, Lavanya, et al.
Publicado: (2022)

Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells
por: Kalaimani, Lavanya, et al.
Publicado: (2022)

Humour
Publicado: (2002)

Humour
por: Association du personnel
Publicado: (2002)

Characterization of the human aqueous humour proteome: A comparison of the genders
por: Perumal, Natarajan, et al.
Publicado: (2017)

Effects of Latanoprost and Bimatoprost on the Expression of Molecules Relevant to Ocular Inflow and Outflow Pathways
por: Li, Xiaohong, et al.
Publicado: (2016)

Inflammatory Molecules in Aqueous Humour and on Ocular Surface and Glaucoma Surgery Outcome
por: Cvenkel, Barbara, et al.
Publicado: (2010)

Aqueous humour cytokine profiles after Descemet’s membrane endothelial keratoplasty
por: Hayashi, Takahiko, et al.
Publicado: (2021)

MicroRNA Profiling of Highly Enriched Human Corneal Epithelial Stem Cells by Small RNA Sequencing
por: Kalaimani, Lavanya, et al.
Publicado: (2020)

The language of humour /
por: Ross, Alison, 1949-
Publicado: (1998)

Humour Me
por: Kelly, Barry
Publicado: (2012)

Allometry and Scaling of the Intraocular Pressure and Aqueous Humour Flow Rate in Vertebrate Eyes
por: Zouache, Moussa A., et al.
Publicado: (2016)

Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics
por: Wierenga, Annemijn P. A., et al.
Publicado: (2019)

Aqueous humour cytokines profiles in eyes with Coats disease and the association with the severity of the disease
por: Liang, Tingyi, et al.
Publicado: (2020)

Factors Predetermining Increased Aqueous Humour Flare in Long-Term Glaucoma Treatment
por: Pakuliene, G., et al.
Publicado: (2020)

Topical bromfenac reduces multiple inflammatory cytokines in the aqueous humour of pseudophakic patients
por: Matsumura, Takehiro, et al.
Publicado: (2021)

The digital aqueous humor outflow meter: an alternative tool for screening of the human eye outflow facility
por: Kozobolis, Vassilios P, et al.
Publicado: (2010)

Awakening the kundalini of humour
por: Shetty, Harish
Publicado: (2006)

The Best of Medical Humour
por: Wilson, M. G.
Publicado: (1991)

Robin's Lectures on the Humours
Publicado: (1875)

Thrombospondin‐1 mediates Rho‐kinase inhibitor‐induced increase in outflow‐facility
por: Shan, Sze‐Wan, et al.
Publicado: (2021)

Non-invasive diagnosis of retinoblastoma using cell-free DNA from aqueous humour
por: Gerrish, Amy, et al.
Publicado: (2019)

Reduced aqueous humour ascorbic-acid concentration in women with smaller anterior chamber depth
por: Ito, Sakae, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jl26n94vtml876raivfi76tpv4