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Activation of the interferon type I response rather than autophagy contributes to myogenesis inhibition in congenital DM1 myoblasts

Congenital myotonic dystrophy type 1 (CDM1) is characterized by severe symptoms that affect patients from birth, with 40% mortality in the neonatal period and impaired skeletal muscle development. In this paper, we examined the relationship between autophagy and abnormal myogenic differentiation of...

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Detalles Bibliográficos
Autores principales: Rizzo, Milena, Beffy, Pascale, Del Carratore, Renata, Falleni, Alessandra, Pretini, Virginia, D’Aurizio, Romina, Botta, Annalisa, Evangelista, Monica, Stoccoro, Andrea, Coppedè, Fabio, Furling, Denis, Simili, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195593/
https://www.ncbi.nlm.nih.gov/pubmed/30341284
http://dx.doi.org/10.1038/s41419-018-1080-1