Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis

Osteoarthritis (OA) is a common joint disorder with increasing impact in an aging society. While genetic and transcriptomic analyses have revealed some genes and non-coding loci associated to OA, the pathogenesis remains incompletely understood. Chromatin profiling, which provides insight into gene...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Chang, Jen-Chien, Hon, Chung-Chau, Fukui, Naoshi, Tanaka, Nobuho, Zhang, Zhenya, Lee, Ming Ta Michael, Minoda, Aki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195601/
https://www.ncbi.nlm.nih.gov/pubmed/30341348
http://dx.doi.org/10.1038/s41598-018-33779-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195601/
https://www.ncbi.nlm.nih.gov/pubmed/30341348
http://dx.doi.org/10.1038/s41598-018-33779-z

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