MicroRNA-495-3p inhibits multidrug resistance by modulating autophagy through GRP78/mTOR axis in gastric cancer

Multidrug resistance (MDR) accounts for poor prognosis in gastric cancer (GC). MicroRNAs (miRNAs) are critical regulators of MDR via modulation of the target genes. The present study revealed that miR-495-3p could act via a target gene, GRP78, to regulate the process of autophagy and inhibit MDR. Ba...

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Detalles Bibliográficos
Autores principales: Chen, Sheng, Wu, Jian, Jiao, Kai, Wu, Qiong, Ma, Jiaojiao, Chen, Di, Kang, Jianqin, Zhao, Guodong, Shi, Yongquan, Fan, Daiming, Zhao, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195618/
https://www.ncbi.nlm.nih.gov/pubmed/30341283
http://dx.doi.org/10.1038/s41419-018-0950-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195618/
https://www.ncbi.nlm.nih.gov/pubmed/30341283
http://dx.doi.org/10.1038/s41419-018-0950-x

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