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Expression pattern of p53-binding protein 1 as a new molecular indicator of genomic instability in bladder urothelial carcinoma

Copy number alterations and loss of heterozygosity are associated with increasing tumor grade and bladder cancer stage. Our previous study suggested that co-expression of Ki-67 and p53-binding protein 1 (53BP1) could provide an indicator of an abnormal DNA damage response (DDR) pathway. The present...

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Detalles Bibliográficos
Autores principales: Matsuda, Katsuya, Kawasaki, Tatsuhiko, Akazawa, Yuko, Hasegawa, Yuhmi, Kondo, Hisayoshi, Suzuki, Keiji, Iseki, Masachika, Nakashima, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195620/
https://www.ncbi.nlm.nih.gov/pubmed/30341375
http://dx.doi.org/10.1038/s41598-018-33761-9