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Expression pattern of p53-binding protein 1 as a new molecular indicator of genomic instability in bladder urothelial carcinoma
Copy number alterations and loss of heterozygosity are associated with increasing tumor grade and bladder cancer stage. Our previous study suggested that co-expression of Ki-67 and p53-binding protein 1 (53BP1) could provide an indicator of an abnormal DNA damage response (DDR) pathway. The present...
Autores principales: | Matsuda, Katsuya, Kawasaki, Tatsuhiko, Akazawa, Yuko, Hasegawa, Yuhmi, Kondo, Hisayoshi, Suzuki, Keiji, Iseki, Masachika, Nakashima, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195620/ https://www.ncbi.nlm.nih.gov/pubmed/30341375 http://dx.doi.org/10.1038/s41598-018-33761-9 |
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