Nanodiamond autophagy inhibitor allosterically improves the arsenical-based therapy of solid tumors

Arsenic trioxide (ATO) is a successful chemotherapeutic drug for blood cancers via selective induction of apoptosis; however its efficacy in solid tumors is limited. Here we repurpose nanodiamonds (NDs) as a safe and potent autophagic inhibitor to allosterically improve the therapeutic efficacy of A...

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Detalles Bibliográficos
Autores principales: Cui, Zhifen, Zhang, Yu, Xia, Kai, Yan, Qinglong, Kong, Huating, Zhang, Jichao, Zuo, Xiaolei, Shi, Jiye, Wang, Lihua, Zhu, Ying, Fan, Chunhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195623/
https://www.ncbi.nlm.nih.gov/pubmed/30341298
http://dx.doi.org/10.1038/s41467-018-06749-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195623/
https://www.ncbi.nlm.nih.gov/pubmed/30341298
http://dx.doi.org/10.1038/s41467-018-06749-2

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