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Src kinase phosphorylates Notch1 to inhibit MAML binding

Notch signaling is a form of intercellular communication which plays pivotal roles at various stages in development and disease. Previous findings have hinted that integrins and extracellular matrix may regulate Notch signaling, although a mechanistic basis for this interaction had not been identifi...

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Detalles Bibliográficos
Autores principales: LaFoya, Bryce, Munroe, Jordan A., Pu, Xinzhu, Albig, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195628/
https://www.ncbi.nlm.nih.gov/pubmed/30341382
http://dx.doi.org/10.1038/s41598-018-33920-y