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Roles for ER:endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation

Multivesicular endosomes/bodies (MVBs) sort membrane proteins between recycling and degradative pathways. Segregation of membrane proteins onto intraluminal vesicles (ILVs) of MVBs removes them from the recycling pathway and facilitates their degradation following fusion of MVBs with lysosomes. Sort...

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Detalles Bibliográficos
Autores principales: Wong, Louise H., Eden, Emily R., Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195632/
https://www.ncbi.nlm.nih.gov/pubmed/30242114
http://dx.doi.org/10.1042/BST20170432