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RAS variant signalling

RAS proteins are small GTPases that regulate signalling networks that control cellular proliferation and survival. They are frequently mutated in cancer and a commonly occurring group of developmental disorders called RASopathies. We discuss recent findings describing how RAS isoforms and different...

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Detalles Bibliográficos
Autores principales: Mo, Stephanie P., Coulson, Judy M., Prior, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195641/
https://www.ncbi.nlm.nih.gov/pubmed/30287508
http://dx.doi.org/10.1042/BST20180173