High cell density fed-batch production of insecticidal recombinant ribotoxin hirsutellin A from Pichia pastoris

BACKGROUND: The fungal ribotoxin hirsutellin A (HtA) exhibits strong insecticidal activity; however, efficient systems for expressing recombinant HtA (rHtA) are lacking. Here, we established an efficient heterologous expression system to produce large amounts of rHtA. RESULTS: Recombinant Pichia pas...

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Detalles Bibliográficos
Autores principales: Li, Hongbo, Xia, Yuxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195745/
https://www.ncbi.nlm.nih.gov/pubmed/30342541
http://dx.doi.org/10.1186/s12934-018-0992-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195745/
https://www.ncbi.nlm.nih.gov/pubmed/30342541
http://dx.doi.org/10.1186/s12934-018-0992-x

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