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Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs

Overcoming multidrug resistance has always been a major challenge in cancer treatment. Recent evidence suggested epithelial-mesenchymal transition plays a role in MDR, but the mechanism behind this link remains unclear. We found that the expression of multiple ABC transporters was elevated in concor...

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Detalles Bibliográficos
Autores principales: Lim, Maegan Miang Kee, Wee, Jonathan Wei Kiat, Soong, Jen Chi, Chua, Damien, Tan, Wei Ren, Lizwan, Marco, Li, Yinliang, Teo, Ziqiang, Goh, Wilson Wen Bin, Zhu, Pengcheng, Tan, Nguan Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195749/
https://www.ncbi.nlm.nih.gov/pubmed/30342537
http://dx.doi.org/10.1186/s12943-018-0904-z