Cargando…
Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs
Overcoming multidrug resistance has always been a major challenge in cancer treatment. Recent evidence suggested epithelial-mesenchymal transition plays a role in MDR, but the mechanism behind this link remains unclear. We found that the expression of multiple ABC transporters was elevated in concor...
Autores principales: | Lim, Maegan Miang Kee, Wee, Jonathan Wei Kiat, Soong, Jen Chi, Chua, Damien, Tan, Wei Ren, Lizwan, Marco, Li, Yinliang, Teo, Ziqiang, Goh, Wilson Wen Bin, Zhu, Pengcheng, Tan, Nguan Soon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195749/ https://www.ncbi.nlm.nih.gov/pubmed/30342537 http://dx.doi.org/10.1186/s12943-018-0904-z |
Ejemplares similares
-
Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin
por: Phua, Terri, et al.
Publicado: (2017) -
Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression
por: Teo, Ziqiang, et al.
Publicado: (2017) -
Angiopoietin-Like 4 Regulates Epidermal Differentiation
por: Pal, Mintu, et al.
Publicado: (2011) -
Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress
por: Chan, Jeremy Soon Kiat, et al.
Publicado: (2017) -
Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia
por: Li, Liang, et al.
Publicado: (2015)