C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two late onset neurodegenerative diseases, have been shown to share overlapping cellular pathologies and genetic origins. Studies suggest that a hexanucleotide repeat expansion in the first intron of the C9orf72 gene is the most...

Descripción completa

Detalles Bibliográficos
Autores principales: Iyer, Shalini, Subramanian, Vasanta, Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195791/
https://www.ncbi.nlm.nih.gov/pubmed/30356970
http://dx.doi.org/10.7717/peerj.5815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195791/
https://www.ncbi.nlm.nih.gov/pubmed/30356970
http://dx.doi.org/10.7717/peerj.5815

Ejemplares similares