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Electroporation-mediated Delivery of FER Gene Enhances Innate Immune Response and Improves Survival in a Murine Model of Pneumonia

Previously, we reported that electroporation-mediated (EP) delivery of the FER gene improved survival in a combined trauma-pneumonia model. The mechanism of this protective effect is unknown. In this paper, we performed a pneumonia model in C57/BL6 mice with 500 CFU of Klebsiella pneumoniae. After i...

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Detalles Bibliográficos
Autores principales: Dolgachev, Vladislav, Panicker, Sreehari, Balijepalli, Sanjay, McCandless, Lane Kelly, Yin, Yue, Swamy, Samantha, Suresh, MV, Delano, Matthew J., Hemmila, Mark R., Raghavendran, Krishnan, Machado-Aranda, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195832/
https://www.ncbi.nlm.nih.gov/pubmed/29907877
http://dx.doi.org/10.1038/s41434-018-0022-y