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Stable and Reproducible Transgene Expression Independent of Proliferative or Differentiated State Using BAC TG-EMBED

Reproducible and stable transgene expression is an important goal in both basic research and biotechnology, with each application demanding a range of transgene expression. Problems in achieving stable transgene expression include multi-copy transgene silencing, chromosome-position effects, and loss...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Pankaj, Zhao, Binhui, Zimmerman, David L., Belmont, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195848/
https://www.ncbi.nlm.nih.gov/pubmed/29930343
http://dx.doi.org/10.1038/s41434-018-0021-z