Sox2 is required for tumor development and cancer cells proliferation in osteosarcoma

The stem cell transcription factor Sox2 is highly expressed in many cancers where it is thought to mark cancer stem cells (CSC). In osteosarcomas, the most common bone malignancy, high Sox2 expression marks and maintains a fraction of tumor initiating cells that show all the properties of CSC. Knock...

Descripción completa

Detalles Bibliográficos
Autores principales: Maurizi, Giulia, Verma, Narendra, Gadi, Abhilash, Mansukhani, Alka, Basilico, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195857/
https://www.ncbi.nlm.nih.gov/pubmed/29743593
http://dx.doi.org/10.1038/s41388-018-0292-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195857/
https://www.ncbi.nlm.nih.gov/pubmed/29743593
http://dx.doi.org/10.1038/s41388-018-0292-2

Ejemplares similares