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Chronological Switch from Translesion Synthesis to Homology-Dependent Gap Repair In Vivo

Cells are constantly exposed to endogenous and exogenous chemical and physical agents that damage their genome by forming DNA lesions. These lesions interfere with the normal functions of DNA such as transcription and replication, and need to be either repaired or tolerated. DNA lesions are accurate...

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Detalles Bibliográficos
Autores principales: Fujii, Shingo, Isogawa, Asako, Fuchs, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195876/
https://www.ncbi.nlm.nih.gov/pubmed/30370004
http://dx.doi.org/10.5487/TR.2018.34.4.297