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IGFBP-5 Promotes Fibrosis via Increasing Its Own Expression and That of Other Pro-fibrotic Mediators

Pulmonary fibrosis is a hallmark of diseases such as systemic sclerosis (SSc, scleroderma) and idiopathic pulmonary fibrosis (IPF). To date, the therapeutic options for patients with pulmonary fibrosis are limited, and organ transplantation remains the most effective option. Insulin-like growth fact...

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Detalles Bibliográficos
Autores principales: Nguyen, Xinh-Xinh, Muhammad, Lutfiyya, Nietert, Paul J., Feghali-Bostwick, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196226/
https://www.ncbi.nlm.nih.gov/pubmed/30374330
http://dx.doi.org/10.3389/fendo.2018.00601