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Novobiocin, a Newly Found TRPV1 Inhibitor, Attenuates the Expression of TRPV1 in Rat Intestine and Intestinal Epithelial Cell Line IEC-6

Background and Purpose: Novobiocin (NOVO), an ABC transporter inhibitor, decreases intestinal wall permeability of capsaicin (CAP), an ABC transporter substrate. However, the mechanism of this effect is not consistent with the action of NOVO as an ABC transporter inhibitor. We previously found that...

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Detalles Bibliográficos
Autores principales: Liang, Qianying, Lv, Xueli, Cai, Qing, Cai, Yun, Zhao, Boxin, Li, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196238/
https://www.ncbi.nlm.nih.gov/pubmed/30374305
http://dx.doi.org/10.3389/fphar.2018.01171