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Twist1-Haploinsufficiency Selectively Enhances the Osteoskeletal Capacity of Mesoderm-Derived Parietal Bone Through Downregulation of Fgf23

Craniofacial development is a program exquisitely orchestrated by tissue contributions and regulation of genes expression. The basic helix–loop–helix (bHLH) transcription factor Twist1 expressed in the skeletal mesenchyme is a key regulator of craniofacial development playing an important role durin...

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Detalles Bibliográficos
Autores principales: Quarto, Natalina, Shailendra, Siny, Meyer, Nathaniel P., Menon, Siddharth, Renda, Andrea, Longaker, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196243/
https://www.ncbi.nlm.nih.gov/pubmed/30374308
http://dx.doi.org/10.3389/fphys.2018.01426