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Twist1-Haploinsufficiency Selectively Enhances the Osteoskeletal Capacity of Mesoderm-Derived Parietal Bone Through Downregulation of Fgf23
Craniofacial development is a program exquisitely orchestrated by tissue contributions and regulation of genes expression. The basic helix–loop–helix (bHLH) transcription factor Twist1 expressed in the skeletal mesenchyme is a key regulator of craniofacial development playing an important role durin...
Autores principales: | Quarto, Natalina, Shailendra, Siny, Meyer, Nathaniel P., Menon, Siddharth, Renda, Andrea, Longaker, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196243/ https://www.ncbi.nlm.nih.gov/pubmed/30374308 http://dx.doi.org/10.3389/fphys.2018.01426 |
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