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Alpha2-Containing Glycine Receptors Promote Neonatal Spontaneous Activity of Striatal Medium Spiny Neurons and Support Maturation of Glutamatergic Inputs

Glycine receptors (GlyRs) containing the α2 subunit are highly expressed in the developing brain, where they regulate neuronal migration and maturation, promote spontaneous network activity and subsequent development of synaptic connections. Mutations in GLRA2 are associated with autism spectrum dis...

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Detalles Bibliográficos
Autores principales: Comhair, Joris, Devoght, Jens, Morelli, Giovanni, Harvey, Robert J., Briz, Victor, Borrie, Sarah C., Bagni, Claudia, Rigo, Jean-Michel, Schiffmann, Serge N., Gall, David, Brône, Bert, Molchanova, Svetlana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196267/
https://www.ncbi.nlm.nih.gov/pubmed/30374290
http://dx.doi.org/10.3389/fnmol.2018.00380