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Analysis of drug resistance in HIV protease

BACKGROUND: Drug resistance in HIV is the major problem limiting effective antiviral therapy. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to select protease mutants for experime...

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Detalles Bibliográficos
Autores principales: Pawar, Shrikant D., Freas, Christopher, Weber, Irene T., Harrison, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196403/
https://www.ncbi.nlm.nih.gov/pubmed/30343664
http://dx.doi.org/10.1186/s12859-018-2331-y