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NDRG2 mRNA levels and miR-28-5p and miR-650 activity in chronic lymphocytic leukemia
BACKGROUND: NDRG2 is identified as a tumor suppressor gene in many tumors, and functions in cell proliferation, differentiation and apoptosis. Recent data indicate that NDRG2 expression is up-regulated by TP53. Moreover, proposed mechanisms of NDRG2 inactivation include epigenetic silencing of the N...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196416/ https://www.ncbi.nlm.nih.gov/pubmed/30348117 http://dx.doi.org/10.1186/s12885-018-4915-3 |