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Metformin in autosomal dominant polycystic kidney disease: experimental hypothesis or clinical fact?

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) accounts for 8–10% of end-stage chronic kidney disease (CKD) patients worldwide. In the last decade, the advanced knowledge in genetics and molecular pathobiology of ADPKD focused some aberrant molecular pathways involved in the pathog...

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Detalles Bibliográficos
Autores principales: Pisani, Antonio, Riccio, Eleonora, Bruzzese, Dario, Sabbatini, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196463/
https://www.ncbi.nlm.nih.gov/pubmed/30348113
http://dx.doi.org/10.1186/s12882-018-1090-3