Submegabase copy number variations arise during cerebral cortical neurogenesis as revealed by single-cell whole-genome sequencing

Somatic copy number variations (CNVs) exist in the brain, but their genesis, prevalence, forms, and biological impact remain unclear, even within experimentally tractable animal models. We combined a transposase-based amplification (TbA) methodology for single-cell whole-genome sequencing with a bio...

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Detalles Bibliográficos
Autores principales: Rohrback, Suzanne, April, Craig, Kaper, Fiona, Rivera, Richard R., Liu, Christine S., Siddoway, Benjamin, Chun, Jerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196524/
https://www.ncbi.nlm.nih.gov/pubmed/30262650
http://dx.doi.org/10.1073/pnas.1812702115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196524/
https://www.ncbi.nlm.nih.gov/pubmed/30262650
http://dx.doi.org/10.1073/pnas.1812702115

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