N-cadherin provides a cis and trans ligand for astrotactin that functions in glial-guided neuronal migration

Prior studies demonstrate that astrotactin (ASTN1) provides a neuronal receptor for glial-guided CNS migration. Here we report that ASTN1 binds N-cadherin (CDH2) and that the ASTN1:CDH2 interaction supports cell–cell adhesion. To test the function of ASTN1:CDH2 binding in glial-guided neuronal migra...

Descripción completa

Detalles Bibliográficos
Autores principales: Horn, Zachi, Behesti, Hourinaz, Hatten, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196552/
https://www.ncbi.nlm.nih.gov/pubmed/30262652
http://dx.doi.org/10.1073/pnas.1811100115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196552/
https://www.ncbi.nlm.nih.gov/pubmed/30262652
http://dx.doi.org/10.1073/pnas.1811100115

Ejemplares similares