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Pitfalls of immunotherapy: lessons from a patient with CTLA-4 haploinsufficiency
BACKGROUND: Daclizumab is a humanized monoclonal antibody that blocks CD25, the high affinity alpha subunit of the interleukin-2 receptor. Daclizumab therapy targets T regulatory cell and activated effector T cell proliferation to suppress autoimmune disease activity, in inflammatory conditions like...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196561/ https://www.ncbi.nlm.nih.gov/pubmed/30377434 http://dx.doi.org/10.1186/s13223-018-0272-7 |