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The DNMT1-associated lincRNA DACOR1 reprograms genome-wide DNA methylation in colon cancer

BACKGROUND: DNA methylation is a key epigenetic mark in mammalian organisms that plays key roles in chromatin organization and gene expression. Although DNA methylation in gene promoters is generally associated with gene repression, recent studies demonstrate that DNA methylation in gene bodies and...

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Detalles Bibliográficos
Autores principales: Somasundaram, Saigopal, Forrest, Megan E, Moinova, Helen, Cohen, Allison, Varadan, Vinay, LaFramboise, Thomas, Markowitz, Sanford, Khalil, Ahmad M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196572/
https://www.ncbi.nlm.nih.gov/pubmed/30348202
http://dx.doi.org/10.1186/s13148-018-0555-3