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Antitumor effects and mechanisms of olaparib in combination with carboplatin and BKM120 on human triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) refers to a heterogeneous group of tumors, for which there is currently a lack of targeted therapies. Poly(ADP-ribose) polymerase (PARP) inhibitors, phosphatidylinositol 3-kinase (PI3K) inhibitors and carboplatin (CBP) have demonstrated sufficient efficacy and sa...

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Detalles Bibliográficos
Autores principales: Zhao, Hui, Yang, Qianxi, Hu, Yunhui, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196642/
https://www.ncbi.nlm.nih.gov/pubmed/30272286
http://dx.doi.org/10.3892/or.2018.6716