Capsaicin and sorafenib combination treatment exerts synergistic anti-hepatocellular carcinoma activity by suppressing EGFR and PI3K/Akt/mTOR signaling

Capsaicin (8-methyl N-vanillyl-6 nonenamide) is a natural plant extract that has antitumor properties and induces apoptosis and autophagy in various types of malignancies, including hepatocellular carcinoma (HCC). Sorafenib is a multi-kinase inhibitor that improves the survival of patients with adva...

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Detalles Bibliográficos
Autores principales: Dai, Ninggao, Ye, Ruifan, He, Qikuan, Guo, Pengyi, Chen, Hao, Zhang, Qiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196646/
https://www.ncbi.nlm.nih.gov/pubmed/30272354
http://dx.doi.org/10.3892/or.2018.6754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196646/
https://www.ncbi.nlm.nih.gov/pubmed/30272354
http://dx.doi.org/10.3892/or.2018.6754

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