Perspective: A Novel Prognostic for Sickle Cell Disease

Sickle hemoglobin (α(2)β(S)(2)) polymerization drives disease pathophysiology in sickle cell anemia. Fetal hemoglobin (α(2)γ(2)) restricts disease severity by inhibiting the polymerization of sickle hemoglobin in a concentration-dependent manner. Clinical decision-making relies on diagnostic technol...

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Detalles Bibliográficos
Autores principales: Mozeleski, Brian M., Al-Rubaish, Abdullah, Al-Ali, Amein, Romero, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Invited Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196691/
https://www.ncbi.nlm.nih.gov/pubmed/30787839
http://dx.doi.org/10.4103/sjmms.sjmms_107_18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196691/
https://www.ncbi.nlm.nih.gov/pubmed/30787839
http://dx.doi.org/10.4103/sjmms.sjmms_107_18

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