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Effects of Dexmedetomidine Postconditioning on Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Role of the PI3K/Akt-Dependent Signaling Pathway

OBJECTIVE: The present study was designed to determine whether dexmedetomidine (DEX) exerts cardioprotection against myocardial I/R injury in diabetic hearts and the mechanisms involved. METHODS: A total of 30 diabetic rats induced by high-glucose-fat diet and streptozotocin (STZ) were randomly assi...

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Detalles Bibliográficos
Autores principales: Cheng, Xiangyang, Hu, Jing, Wang, Ya, Ye, Hongwei, Li, Xiaohong, Gao, Qin, Li, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196799/
https://www.ncbi.nlm.nih.gov/pubmed/30402501
http://dx.doi.org/10.1155/2018/3071959