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First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

OBJECTIVE: Latent autoimmune diabetes in adults (LADA) shares clinical features with both type 1 and type 2 diabetes; however, there is ongoing debate regarding the precise definition of LADA. Understanding its genetic basis is one potential strategy to gain insight into appropriate classification o...

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Detalles Bibliográficos
Autores principales: Cousminer, Diana L., Ahlqvist, Emma, Mishra, Rajashree, Andersen, Mette K., Chesi, Alessandra, Hawa, Mohammad I., Davis, Asa, Hodge, Kenyaita M., Bradfield, Jonathan P., Zhou, Kaixin, Guy, Vanessa C., Åkerlund, Mikael, Wod, Mette, Fritsche, Lars G., Vestergaard, Henrik, Snyder, James, Højlund, Kurt, Linneberg, Allan, Käräjämäki, Annemari, Brandslund, Ivan, Kim, Cecilia E., Witte, Daniel, Sørgjerd, Elin Pettersen, Brillon, David J., Pedersen, Oluf, Beck-Nielsen, Henning, Grarup, Niels, Pratley, Richard E., Rickels, Michael R., Vella, Adrian, Ovalle, Fernando, Melander, Olle, Harris, Ronald I., Varvel, Stephen, Grill, Valdemar E.R., Hakonarson, Hakon, Froguel, Philippe, Lonsdale, John T., Mauricio, Didac, Schloot, Nanette C., Khunti, Kamlesh, Greenbaum, Carla J., Åsvold, Bjørn Olav, Yderstræde, Knud B., Pearson, Ewan R., Schwartz, Stanley, Voight, Benjamin F., Hansen, Torben, Tuomi, Tiinamaija, Boehm, Bernhard O., Groop, Leif, Leslie, R. David, Grant, Struan F.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196829/
https://www.ncbi.nlm.nih.gov/pubmed/30254083
http://dx.doi.org/10.2337/dc18-1032