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Arrhythmogenic Mechanisms in Heart Failure: Linking β-Adrenergic Stimulation, Stretch, and Calcium

Heart failure (HF) is associated with elevated sympathetic tone and mechanical load. Both systems activate signaling transduction pathways that increase cardiac output, but eventually become part of the disease process itself leading to further worsening of cardiac function. These alterations can ad...

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Detalles Bibliográficos
Autores principales: Johnson, Daniel M., Antoons, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196916/
https://www.ncbi.nlm.nih.gov/pubmed/30374311
http://dx.doi.org/10.3389/fphys.2018.01453