Cargando…
Arrhythmogenic Mechanisms in Heart Failure: Linking β-Adrenergic Stimulation, Stretch, and Calcium
Heart failure (HF) is associated with elevated sympathetic tone and mechanical load. Both systems activate signaling transduction pathways that increase cardiac output, but eventually become part of the disease process itself leading to further worsening of cardiac function. These alterations can ad...
Autores principales: | Johnson, Daniel M., Antoons, Gudrun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196916/ https://www.ncbi.nlm.nih.gov/pubmed/30374311 http://dx.doi.org/10.3389/fphys.2018.01453 |
Ejemplares similares
-
Mechanotransduction and Adrenergic Stimulation in Arrhythmogenic Cardiomyopathy: An Overview of in vitro and in vivo Models
por: Beffagna, Giorgia, et al.
Publicado: (2020) -
Arrhythmogenic Interaction Between Sympathetic Tone and Mechanical Stretch in Rat Pulmonary Vein Myocardium
por: Egorov, Yuriy V., et al.
Publicado: (2020) -
Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy
por: Cannavo, Alessandro, et al.
Publicado: (2013) -
Editorial: The Role of Calcium Handling in Heart Failure and Heart Failure Associated Arrhythmias
por: Johnson, Daniel M., et al.
Publicado: (2019) -
Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac Ca(V)1.2 calcium channel
por: Hovey, Liam, et al.
Publicado: (2023)