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Increased CCR7(lo)PD-1(hi)CXCR5(+)CD4(+) T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection

T follicular helper cells (Tfh cells) affect essential immune pathogenesis in chronic hepatitis B virus (HBV) infection. The CCR7(lo)PD-1(hi) Tfh subset has a partial Tfh effector phenotype and is associated with active Tfh differentiation, whereas the CCR7(hi)PD-1(lo) Tfh subset is a resting phenot...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Xin, Zhao, Qi-Yi, Wu, Li-Li, Xie, Dong-Ying, Gao, Zhi-Liang, Deng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196997/
https://www.ncbi.nlm.nih.gov/pubmed/30402448
http://dx.doi.org/10.1155/2018/1020925