Cargando…

Increased CCR7(lo)PD-1(hi)CXCR5(+)CD4(+) T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection

T follicular helper cells (Tfh cells) affect essential immune pathogenesis in chronic hepatitis B virus (HBV) infection. The CCR7(lo)PD-1(hi) Tfh subset has a partial Tfh effector phenotype and is associated with active Tfh differentiation, whereas the CCR7(hi)PD-1(lo) Tfh subset is a resting phenot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Ya-Xin, Zhao, Qi-Yi, Wu, Li-Li, Xie, Dong-Ying, Gao, Zhi-Liang, Deng, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196997/ https://www.ncbi.nlm.nih.gov/pubmed/30402448 http://dx.doi.org/10.1155/2018/1020925

Ejemplares similares

CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells are positively correlated with levels of IL-21 in active and transitional cystic echinococcosis patients
por: Zhang, Fengbo, et al.
Publicado: (2015)

Increased levels of CCR7(lo)PD-1(hi) CXCR5(+) CD4(+) T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure
por: Gong, Qiaoqiao, et al.
Publicado: (2017)

Rhesus Macaque Lymph Node PD-1(hi)CD4(+) T Cells Express High Levels of CXCR5 and IL-21 and Display a CCR7(lo)ICOS(+)Bcl6(+) T-Follicular Helper (Tfh) Cell Phenotype
por: Onabajo, Olusegun O., et al.
Publicado: (2013)

Circulating CCR7(lo)PD-1(hi) Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sjögren's Syndrome
por: Kim, Ji-Won, et al.
Publicado: (2019)

Tumors exploit CXCR4(hi)CD62L(lo) aged neutrophils to facilitate metastatic spread
por: Peng, Zhenzi, et al.
Publicado: (2021)

Circulating CXCR5(−)PD-1(hi) peripheral T helper cells are associated with progression to type 1 diabetes
por: Ekman, Ilse, et al.
Publicado: (2019)

Characteristics and PD-1 expression of peripheral CD4(+)CD127(lo)CD25(hi)FoxP3(+ )Treg cells in chronic HCV infected-patients
por: Shen, Tao, et al.
Publicado: (2011)

CCR3, CCR4, CCR5, and CXCR3 expression in peripheral blood CD4+ lymphocytes in gastric cancer patients
por: Andalib, Alireza, et al.
Publicado: (2013)

Chemokine Receptors CCR1 and CCR2 on Peripheral Blood Mononuclear Cells of Newly Diagnosed Patients with the CD38-Positive Chronic Lymphocytic Leukemia
por: Kholodnyuk, Irina, et al.
Publicado: (2020)

The signature of HBV-related liver disease in peripheral blood mononuclear cell DNA methylation
por: Li, Kang, et al.
Publicado: (2020)

The HIV-1 Gp120/CXCR4 Axis Promotes CCR7 Ligand-Dependent CD4 T Cell Migration: CCR7 Homo- and CCR7/CXCR4 Hetero-Oligomer Formation as a Possible Mechanism for Up-Regulation of Functional CCR7
por: Hayasaka, Haruko, et al.
Publicado: (2015)

CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver
por: Stegmann, Kerstin A., et al.
Publicado: (2016)

Increased frequency of PD-1(hi)CXCR5(-) T cells and B cells in patients with newly diagnosed IgA nephropathy
por: Wang, Xin, et al.
Publicado: (2020)

The Regulation between CD4(+)CXCR5(+) Follicular Helper T (Tfh) Cells and CD19(+)CD24(hi)CD38(hi) Regulatory B (Breg) Cells in Gastric Cancer
por: Zhang, Ying, et al.
Publicado: (2022)

Prognostic value of immunoexpression of CCR4, CCR5, CCR7 and CXCR4 in squamous cell carcinoma of tongue and floor of the mouth
por: Domingueti, Catherine-Bueno, et al.
Publicado: (2019)

PD-1(high)CXCR5(–)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection
por: Asashima, Hiromitsu, et al.
Publicado: (2023)

CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren’s Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells
por: Hinrichs, Anneline C., et al.
Publicado: (2023)

Accumulation of CCR4(+) CTLA-4(hi) FOXP3(+)CD25(hi) Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells
por: Svensson, Helena, et al.
Publicado: (2012)

Distinctive pattern of AHNAK methylation level in peripheral blood mononuclear cells and the association with HBV‐related liver diseases
por: Sun, Libo, et al.
Publicado: (2018)

CCR2 Deficiency Impairs Ly6C(lo) and Ly6C(hi) Monocyte Responses in Orientia tsutsugamushi Infection
por: Petermann, Michael, et al.
Publicado: (2021)

Establishment of a novel CCR5 and CXCR4 expressing CD4(+ )cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists
por: Princen, Katrien, et al.
Publicado: (2004)

Characterization of splenic MRC1(hi)MHCII(lo) and MRC1(lo)MHCII(hi) cells from the monocyte/macrophage lineage of White Leghorn chickens
por: Yu, Keesun, et al.
Publicado: (2020)

Potential diagnostic value of PD‐1 in peripheral blood mononuclear cells of postmenopausal osteoporosis patients
por: Cai, Xiu‐Ping, et al.
Publicado: (2020)

Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing
por: Mcheik, Saria, et al.
Publicado: (2019)

Murine CXCR3(+)CXCR6(+)γδT Cells Reside in the Liver and Provide Protection Against HBV Infection
por: Wang, Yanan, et al.
Publicado: (2022)

The diagnostic role of PD‐1(+) CXCR5(+) follicular helper CD8(+) T cell in renal allograft dysfunction
por: Fan, Ji‐wen, et al.
Publicado: (2021)

CXCR4(hi) effector neutrophils in sickle cell anemia: potential role for elevated circulating serotonin (5-HT) in CXCR4(hi) neutrophil polarization
por: Garcia, Flavia, et al.
Publicado: (2020)

Overexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells
por: Nami, Babak, et al.
Publicado: (2016)

Percentage of Peripheral CD19+CD24hiCD38hi Regulatory B Cells in Neonatal Sepsis Patients and Its Functional Implication
por: Pan, Xiao, et al.
Publicado: (2016)

PD1(hi) CD200(hi) CD4(+) exhausted T cell increase immunotherapy resistance and tumour progression by promoting epithelial–mesenchymal transition in bladder cancer
por: Wu, Chun, et al.
Publicado: (2023)

Effect of Cannabidiol on Human Peripheral Blood Mononuclear Cells and CD4+ T Cells
por: Furgiuele, Alessia, et al.
Publicado: (2023)

Immunomodulation Induced During Interferon-α Therapy Impairs the Anti-HBV Immune Response Through CD24(+)CD38(hi) B Cells
por: Fu, Binqing, et al.
Publicado: (2020)

PD-1 blockade restores helper activity of tumor-infiltrating, exhausted PD-1(hi)CD39(+) CD4 T cells
por: Balança, Camille-Charlotte, et al.
Publicado: (2021)

CTLA4(+)CD4(+)CXCR5(−)FOXP3(+) T cells associate with unfavorable outcome in patients with chronic HBV infection
por: Wen, Chunhua, et al.
Publicado: (2023)

CD19(+)CD24(hi)CD38(hi) B Cell Dysfunction in Primary Biliary Cholangitis
por: Chen, Qubo, et al.
Publicado: (2020)

CXCR5(+)PD-1(+) follicular helper CD8 T cells control B cell tolerance
por: Chen, Yuhong, et al.
Publicado: (2019)

Mineralocorticoid receptor signaling reduces numbers of circulating human naïve T cells and increases their CD62L, CCR7, and CXCR4 expression
por: Besedovsky, Luciana, et al.
Publicado: (2014)

CD3e-immunotoxin spares CD62L(lo) Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3e(hi) T cells
por: Kim, Shihyoung, et al.
Publicado: (2022)

Functional Exhaustion of HBV-Specific CD8 T Cells Impedes PD-L1 Blockade Efficacy in Chronic HBV Infection
por: Ferrando-Martinez, Sara, et al.
Publicado: (2021)

Divergent Expression of CXCR5 and CCR5 on CD4(+) T Cells and the Paradoxical Accumulation of T Follicular Helper Cells during HIV Infection
por: Zaunders, John, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_u81lovrqrf4i153mt74huh6bfu