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Disubstituted piperazine analogues of trifluoromethylphenylpiperazine and methylenedioxybenzylpiperazine: analytical differentiation and serotonin receptor binding studies

A series of N,N-disubstituted piperazines were synthesized containing the structural elements of both methylenedioxybenzylpiperazine (MDBP) and trifluoromethylphenylpiperazine (TFMPP) in a single molecule. These six potential designer drug molecules having a regioisomeric relationship were compared...

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Detalles Bibliográficos
Autores principales: DeRuiter, Jack, Van Cleave, Ashleigh, de Sousa Moura, Audinei, Abiedalla, Younis, Clark, C. Randall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197089/
https://www.ncbi.nlm.nih.gov/pubmed/30483665
http://dx.doi.org/10.1080/20961790.2018.1445497