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Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation
BACKGROUND: Despite compelling data describing pro-regenerative effects of all-trans retinoic acid (ATRA) in pre-clinical models of chronic obstructive pulmonary disease (COPD), clinical trials using retinoids for emphysema patients have failed. Crucial information about the specific role of RA sign...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197151/ https://www.ncbi.nlm.nih.gov/pubmed/30236449 http://dx.doi.org/10.1016/j.ebiom.2018.09.002 |