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Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation

BACKGROUND: Despite compelling data describing pro-regenerative effects of all-trans retinoic acid (ATRA) in pre-clinical models of chronic obstructive pulmonary disease (COPD), clinical trials using retinoids for emphysema patients have failed. Crucial information about the specific role of RA sign...

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Detalles Bibliográficos
Autores principales:	Ng-Blichfeldt, John-Poul, Schrik, Anneke, Kortekaas, Rosa K., Noordhoek, Jacobien A., Heijink, Irene H., Hiemstra, Pieter S., Stolk, Jan, Königshoff, Melanie, Gosens, Reinoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197151/ https://www.ncbi.nlm.nih.gov/pubmed/30236449 http://dx.doi.org/10.1016/j.ebiom.2018.09.002

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