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Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients
Circulating tumor DNA (ctDNA) offers new opportunities for noninvasive cancer management. Detecting ctDNA in plasma is challenging because it constitutes only a minor fraction of the total cell-free DNA (cfDNA). Pre-analytical factors affect cfDNA levels contributed from leukocyte lysis, hence the a...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Investigative Pathology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197164/ https://www.ncbi.nlm.nih.gov/pubmed/30165204 http://dx.doi.org/10.1016/j.jmoldx.2018.07.005 |