Effects of Collection and Processing Procedures on Plasma Circulating Cell-Free DNA from Cancer Patients

Circulating tumor DNA (ctDNA) offers new opportunities for noninvasive cancer management. Detecting ctDNA in plasma is challenging because it constitutes only a minor fraction of the total cell-free DNA (cfDNA). Pre-analytical factors affect cfDNA levels contributed from leukocyte lysis, hence the a...

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Detalles Bibliográficos
Autores principales: Risberg, Bente, Tsui, Dana W.Y., Biggs, Heather, Ruiz-Valdepenas Martin de Almagro, Andrea, Dawson, Sarah-Jane, Hodgkin, Charlotte, Jones, Linda, Parkinson, Christine, Piskorz, Anna, Marass, Francesco, Chandrananda, Dineika, Moore, Elizabeth, Morris, James, Plagnol, Vincent, Rosenfeld, Nitzan, Caldas, Carlos, Brenton, James D., Gale, Davina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197164/
https://www.ncbi.nlm.nih.gov/pubmed/30165204
http://dx.doi.org/10.1016/j.jmoldx.2018.07.005

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