Inhibition of glucose metabolism selectively targets autoreactive follicular helper T cells

Follicular helper T (T(FH)) cells are expanded in systemic lupus erythematosus, where they are required to produce high affinity autoantibodies. Eliminating T(FH) cells would, however compromise the production of protective antibodies against viral and bacterial pathogens. Here we show that inhibiti...

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Detalles Bibliográficos
Autores principales: Choi, Seung-Chul, Titov, Anton A., Abboud, Georges, Seay, Howard R., Brusko, Todd M., Roopenian, Derry C., Salek-Ardakani, Shahram, Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197193/
https://www.ncbi.nlm.nih.gov/pubmed/30348969
http://dx.doi.org/10.1038/s41467-018-06686-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197193/
https://www.ncbi.nlm.nih.gov/pubmed/30348969
http://dx.doi.org/10.1038/s41467-018-06686-0

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